MOQ is a no. My typical workaround is to add a custom field on the item level indicating the MOQ and a dashboard alert for when order lines are below that MOQ.
The only way to utilize multiples for Supply Planning/Planning Workbench is by utilizing a Fixed Lot Size, this cannot be utilized in conjunction with Periods of Supply though (If you're using Lot for Lot and need multiples, then Fixed Lot Size is the way to go)