Anyone have any experience with this sort of thing?

@XochisSketches At my last company, we didn't switch datacenters, but had a fair bit of challenge with the sandbox domain change because of our heavily scripted environment. The coding theoretically shouldn't be too hard, since it's pretty easy to ctrl+f for hard-coded URLs, but it's still real easy for someone to miss something important. Talk to your developers and then test, test, and test some more. Ultimately testing is the only real safeguard. Definitely call NS support and see if they can point one of your sandboxes to the new datacenter so you can easily do the aforementioned testing (I'm assuming this is possible, but not sure on that point).

@James Morris Sandboxes are currently hosted in Europe, yes?

@XochisSketches Not sure. My understanding was that they're in the same datacenter as your production account typically, but I could be wrong. I was referring to when they moved sandboxes off of system.sandbox.netsuite.com