Hello, I have a question. Is there a way to do multi-drop ship PO's for each sales order line? Thank you

Only if different vendor supplies items on the sales order.

I have not tested it, but wonder if this could be a potential solution. If you have multiple lines with quantities for each drop-ship, do not have preferred vendor for the item(s) so that not all lines automatically go to the same vendor's PO when creating a drop-ship PO.