Generally yes. If you can't do so, it might be because:
1. There's a workflow/script running locking the record and/or that field
2. The entry originated from a different module's process (allocations, amortization etc) where I've seen the amount field be locked/grayed out
Note that if you modify one amount, you'll likely have to modify at least one other so that the debits and credits match and you're in balance between subsidiaries.