We're about 2 years into using NetSuite. I'm in process of decluttering unnecessary saved searches. Is NetSuite One Implementation Bundle 39609 safe to uninstall or is it going to blow the system up? We haven't done any implementation items for over a year now.

you should look through the contents of those records and see if that is something you can loose. Usually there are great notes and issue logs that are worthwhile to hold on to,