Anyone know if it's possible to configure company or accounting preferences through the REST API? We would like to incorporate this into our end-to-end tests, to avoid UI interactions. In other words, is configuration a UI only thing?

Check out the n/config module

Thanks @zach. I got it figured out for the preferences, but I'm getting errors trying to set Features (enable features). Mostly

ACCESS_DENIED : Access to this configuration is denied.  Please contact NetSuite to gain access to this configuration.