Or, what might work a bit better, is if you were to create a custom check box field on the Sales Order that denotes a refund is needed. Following the creation of the checkbox and placing it on the sales order, you can create a workflow that will distribute an email upon saving that can be sent to the higher up 's in the accounting department letting them know that they need to create a customer refund for that order.
There's also an ability to allow employees to ONLY create refunds*,* which is probably fine to use if you have approval routing turned on. This will keep them all in a non-posting pool that will only post and be approved once someone with proper permission has verified the refund is legitimate and accurate.