Since you are looking at save on orders... Here's a tip: If you have a beforesubmit script that edits the item sublist in any way, the lines will need to be recalculated and that extra time will also show up as Netsuite system-time even if it is directly related to the script.
In the page time details, you will notice as a rather large gap right after the beforesubmit-script and any other beforesubmit-actions. Sometimes I've added a small beforesubmit-script that only logs after an existing one just to see that gap.