On a saved search, is it possible to highlight a certain column or individual "cell" (result) instead of highlighting the entire row?

yes with a formula html field, for example: CASE WHEN {field1} = '1' THEN 'p style="background-color:#000000"'||{value}||'' WHEN {field1} = '2 ' THEN 'p style="background-color:#FFFFFF"'||{value}||'' ELSE {value} END