When using Redwood theme I can't change the colors in my preferences. That's bad because I use colors to set apart Production and Sandbox accounts 😞 Colors, fonts, and chart palettes are included, so those preferences are grayed out. You can always go back to your old color theme by disabling Redwood experience.

As far as Colors go no, it is by design that when you enable Redwood it disables the Colors option. There is currently no way to have Redwood enabled and use different colors. It was the number one thing everyone was complaining about in the Release Preview webinar. Especially given that is the best practice NetSuite advise!