In our organization, we do a lot of cross-departmental charges which causes us to change the department per line on expenses reports because of departmental restrictions. Does anyone know a good way to process cross-departmental charges in NetSuite when restricting employees to their department?

So you don't permit the employee entering the exprpt to change the department? How do you determine what department should be changed to, when reviewing/approving? Is each line on the exprpt for one purchase benefitting a single department, or are you actually trying to allocate one purchase across multiple departments?

We restrict the employee's role to their department so they can't see other departments transactions. Causes them not to be able to select other departments in expense reports. If the user wants to charge another department it puts that information in the Memo field then the reviewer changes the deaprtment. Each line is a single expense that should be charged to a single department.

Given what you've set up I don't see a good way to allow the user to change it without altering the role. You'd have to move the restriction on the users to a different place (i.e user's role is not restricted but Department field is inline on all transactions except expense reports).