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I am using the nlapiDisableLineItemField to disable the rate column field on line item through client script.But is is not working. Please help

You should give more information. E.g. your code

nlapiDisableLineItemField('item','quantity',true); using Pageinit

you wont have much disabling those kind of fields

netsuite will undisable native fields it uses for sourcing

you can try disabling it after every postSourcing event, but I would hide the field