If the search is going to be triggered or run by an User through the UI, the cleanest way I can think of is to have a Suitelet where that user will see/trigger that search and from there you can do what you want... you are going to be basically replacing the normal UI/access to the search for a Suitelet... telling the user that to see that search should be through this link(suitelet link...)

@alien4u that sound like a very interesting approach.

👍

It will be a pretty complicated suitelet, if indeed you want to keep all the netsuite native functionality like filters, inline edit etc'

You could have the suitelet update the necessary fields and then forward you to the saved search. That will then show those updates since it would be loaded after those updates are performed.