If I want to automatically update the custom fields in the drop ship PO when I edit the drop ship SO, is it possible only through scripting? Upon creation, I can populate the drop ship PO custom fields automatically.

Depending on the fields and the source of the data to be updated you might be able to use a workflow

The source is the linked drop ship SO while the destination is the linked drop ship PO. Not sure how to trigger the PO when there's a change in the related SO.

It would have to be a scheduled workflow. The most it could run would be every 30 min Use the applied to transaction join to pull the values from the SO you want

Thank you! I guess we would have to script it because these are time-sensitive data.